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American Society of Microbiology ABMM Study Reference - ABMM Associate Level Exam

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American Society of Microbiology ABMM Sample Questions (Q27-Q32):

NEW QUESTION # 27
A microbiology laboratory isolates a Gram-negative rod from a wound infection. The organism is oxidase- negative, ferments lactose on MacConkey agar, and produces indole. The MOST likely identification is:

A. Serratia marcescens
B. Klebsiella pneumoniae
C. Escherichia coli
D. Proteus mirabilis

Answer: C

NEW QUESTION # 28
A clinical microbiology laboratory is monitoring the emergence of resistance to colistin in Gram-negative bacteria. Resistance to colistin is often mediated by modifications of the bacterial lipopolysaccharide (LPS).
The genetic basis for acquired colistin resistance most commonly involves:

A. Acquisition of genes encoding efflux pumps that specifically target colistin.
B. Production of enzymes that directly inactivate the colistin molecule.
C. Alterations in the outer membrane porin proteins, reducing colistin uptake.
D. Mutations in genes encoding enzymes that modify the lipid A component of LPS.

Answer: D

NEW QUESTION # 29
A clinical microbiology laboratory is using CRISPR-based technology for rapid and sensitive detection of specific bacterial DNA sequences directly from patient samples. This method relies on the ability of the Cas enzyme to:

A. Specifically bind to and cleave target DNA sequences guided by a short RNA molecule.
B. Amplify target DNA sequences using specific primers and thermal cycling.
C. Detect the presence of specific antibodies produced in response to bacterial infection.
D. Reverse transcribe RNA into complementary DNA.

Answer: A

NEW QUESTION # 30
Which serological marker pattern is most consistent with chronic Hepatitis B virus infection with high infectivity?

A. HBsAg (-), Anti-HBs (+), Anti-HBc Total (-), IgM Anti-HBc (-), HBeAg (-), Anti-HBe (-)
B. HBsAg (+), Anti-HBs (-), Anti-HBc Total (+), IgM Anti-HBc (-), HBeAg (+), Anti-HBe (-)
C. HBsAg (-), Anti-HBs (+), Anti-HBc Total (+), IgM Anti-HBc (-), HBeAg (-), Anti-HBe (+)
D. HBsAg (+), Anti-HBs (-), Anti-HBc Total (+), IgM Anti-HBc (+), HBeAg (+), Anti-HBe (-)

Answer: B

NEW QUESTION # 31
Clavulanic acid is often combined with amoxicillin (e.g., Augmentin™) to overcome certain types of bacterial resistance. What is the primary mechanism by which clavulanic acid enhances amoxicillin's activity?

A. It inhibits bacterial efflux pumps that would otherwise remove amoxicillin from the cell.
B. It binds to alternative penicillin-binding proteins (PBPs), providing a synergistic bactericidal effect.
C. It functions as a potent, irreversible inhibitor of many bacterial beta-lactamase enzymes.
D. It increases the outer membrane permeability to amoxicillin in Gram-negative bacteria.

Answer: C

NEW QUESTION # 32
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